摘要 |
4-thionaphthyl-1H-imidazoles are alpha 2-adrenoceptor agonists/antagonists. As delta-opioid receptor agonists, such compounds are useful as analgesics. Depending on their agonist/antagonist effect, such compounds may also be useful agents to treat hypertension, glaucoma, sexual dysfunction, depression, attention deficit hyperactivity disorder, the need for anesthesia or cardiac arrythmia.
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申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
BAXTER, ELLEN, W.;BOYD, ROBERT, E.;JETTER, MICHELLE, C.;MCDONNELL, MARK;REITZ, ALLEN, B.;ROSS, TINA, MORGAN |