发明名称 |
METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS |
摘要 |
The present invention relates to the mammalian Hcen-2 gene. The invention relates to methods for the identification of compounds that modulate the expression of Hcen-2 and to using such compounds as therapeutic agents in the treatment of Hcen-2 disorders. The invention also relates to methods for the diagnostic evaluation, genetic testing and prognosis of Hcen-2 mediated disorders, and to methods and compositions for the treatment of these disorders. The invention also relates to use of the Hcen-2 gene and/or gene products as markers for fine structure mapping of a region of human chromosome 18, including a region of the chromosome involved in mediating neuropsychiatric disorders.
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申请公布号 |
CA2327652(A1) |
申请公布日期 |
1999.10.14 |
申请号 |
CA19992327652 |
申请日期 |
1999.04.05 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
FREIMER, NELSON B.;CHEN, HONG |
分类号 |
G01N33/50;A61K45/00;A61P25/00;C07K5/00;C07K14/00;C07K16/00;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/68;(IPC1-7):C12Q1/68;C07H21/04;C12N15/63;C12N15/85;C12N15/86 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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