For the oral administration of the anti-depressant mirtazapine an aqueous solution or suspension is found which is preferably stabilised by methionine, is thickened, and which has a pH of from 2.5 to 3. By the formulation according to the invention, an undesirable local anaesthetic effect of mirtazapine is avoided.
申请公布号
WO9951237(A1)
申请公布日期
1999.10.14
申请号
WO1999EP02277
申请日期
1999.03.29
申请人
AKZO NOBEL N.V.;SKRABANJA, ARNOLD, TITUS, PHILIP;TULLY, ROGER, EDWARD
发明人
SKRABANJA, ARNOLD, TITUS, PHILIP;TULLY, ROGER, EDWARD