<p>A method of gene synthesis is disclosed. The gene synthesis method permits the codons of [m] natural gene to be changed to allow preferential transcription and translation of the synthetic gene in transgenic organisms. The method utilizes a combination of enzymatic and chemical synthesis of DNA and significantly reduces the cost, time and number of steps required for construction of synthetic genes.</p>
申请公布号
EP0948626(A2)
申请公布日期
1999.10.13
申请号
EP19970945060
申请日期
1997.10.06
申请人
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG;RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD.