发明名称 |
PROTEINS OF THE NOTCH FAMILY, GENES AND LIGANDS THEREOF |
摘要 |
<p>The present invention relates to the use of therapeutic compounds in the modification of T-cell, T-cell-antigen presenting cell (APC) interactions and the interactions between pathogenic organisms and immunocompetent cells of a host. In particular it relates to the use of these compounds in the modulation of the interaction between Notch proteins and their ligands and to the use of such compounds in the therapy of conditions such as graft rejection, autoimmunity, allergy, and asthma and infectious diseases.</p> |
申请公布号 |
CZ9901639(A3) |
申请公布日期 |
1999.10.13 |
申请号 |
CZ19990001639 |
申请日期 |
1997.11.06 |
申请人 |
LORANTIS LIMITED |
发明人 |
LAMB JONATHAN ROBERT;DALLMAN MARGARET JANE;HOYNE GERALD FRANCIS |
分类号 |
C12N15/02;A61K38/00;A61K39/00;A61K45/00;A61P1/16;A61P31/04;A61P31/20;A61P33/00;A61P33/06;A61P37/02;A61P37/04;A61P37/06;A61P37/08;C07K14/705;C07K14/725;C07K16/28;C07K19/00;C12N5/18;C12N15/63;G01N33/50;G01N33/68;(IPC1-7):C12N15/63;C12N15/85;G01N33/53;A61K38/17 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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