发明名称 |
Derivatives of 2-fluoro 3-de(2,6-dideoxy 3-C-methyl-3-0-methyl-alpha-L-ribohexopyranosyl oxy) 6-1-methyl 3-oxo erythromycin, their process of preparation and application in the synthesis of medicaments |
摘要 |
<p>2-Fluoro-3-de((2,6-dideoxy-3-C-methyl-3-O-methyl- alpha -L-ribo-hexopyranosyl)oxy)6-O-methyl-3-oxo-erythromycin derivatives (I) and their salts are new. 2-Fluoro-3-de((2,6-dideoxy-3-C-methyl-3-O-methyl- alpha -L-ribo-hexopyranosyl)oxy)6-O-methyl-3-oxo-erythromycin derivatives of formula (I) and their salts are new. A = OH; B + carbon in position 10 = double bond; A + B = carbonate or carbamate; and OZ = OH, ester or ether. Independent claims are also included for: (1) the preparation of (I); and (2) the derivatives of formula (II) obtained from (I), and intermediates of (I: A + B = O-CO-NR; R = not defined).</p> |
申请公布号 |
EP0949268(A1) |
申请公布日期 |
1999.10.13 |
申请号 |
EP19990400843 |
申请日期 |
1999.04.07 |
申请人 |
HOECHST MARION ROUSSEL |
发明人 |
BONNET, ALAIN;GAMBIER, FRANCOISE |
分类号 |
C07H17/08;(IPC1-7):C07H17/08 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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