| 摘要 |
IgE antagonists comprising one or more of the Fc epsilon RI receptor-binding determinant sites of human IgE are described. The disclosed antagonists include IgE variants, peptide antagonists, peptidomimetics and other small molecules. The antagonists are useful in raising and screening anti-IgE antibodies, in the isolation and purification of Fc epsilon RI receptor, and in the treatment of allergic disease. |
