发明名称 |
Treatment of preeclampsia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor |
摘要 |
Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both, optionally in further combination with one or more of a cyclooxygenase inhibitor, a PGI2-mimetic, a thromboxane (TXA2) inhibitor, a compound possessing TXA2-agonistic and TXA2-inhibiting properties, a compound possessing TXA2-antagonistic and PGI2-memetic activities, and a TXA2 antagonist.
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申请公布号 |
US5965529(A) |
申请公布日期 |
1999.10.12 |
申请号 |
US19950466688 |
申请日期 |
1995.06.06 |
申请人 |
THE BOARD OF REGENTS, UNIVERSITY OF TEXAS;SCHERING AKTIENGESELLSCHAFT |
发明人 |
GARFIELD, ROBERT E.;CHWALISZ, KRZYSZTOF;BUKOWSKI, RADOSLAW;YALLAMP'AL LI, CHANDRA |
分类号 |
A61K31/04;A61K31/195;A61K31/198;A61K31/295;A61K31/341;A61K31/565;A61K31/57;A61K31/60;A61P13/02;A61P15/00;A61P15/06;(IPC1-7):A61K33/26;A61K31/21;A61K38/00;A01N59/24 |
主分类号 |
A61K31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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