发明名称 |
Lactobacillus salivarius stamme, helsebringende produkt, antimikrobielt middel, samt anvendelser derav og DNA-sekvens |
摘要 |
A strain of Lactobacillus salivarius isolated from resected and washed human gastrointestinal tract inhibits a broad range of Gram positive and Gram negative microorganisms and secretes a product having antimicrobial activity into a cell-free supernatant. The activity is produced only by growing cells and is destroyed by proteinase K and pronase E, the inhibitory properties of the strain and its secretory products being maintained in the presence of physiological concentrations of human bile and human gastric juice. The strain exhibits a broad-spectrum of activity against bacteria including Listeria, Staphylococcus, including methocillin resistant St. aureus (MRSA), and Bacillus, but does not inhibit many closely related lactobacilli. An antimicrobial agent is obtained from the strain which has bacteriocin-like properties. |
申请公布号 |
NO993818(A) |
申请公布日期 |
1999.10.11 |
申请号 |
NO19990003818 |
申请日期 |
1999.08.06 |
申请人 |
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK |
发明人 |
COLLINS, JOHN KEVIN;THORNTON, GERARDINE MARY;O'SULLIVAN, GERALD CHRISTOPHER;O'SULLIVAN, MARIAN MARY GERALDINE |
分类号 |
A23C9/12;C12N1/20;A23L1/03;A23L1/28;A61K35/74;A61K38/00;A61P31/04;C07K14/335;C12N1/00;C12N15/09;C12N15/31;C12R1/225 |
主分类号 |
A23C9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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