发明名称 |
Induction and enhancement of the immune response to type-2 t cell-independent antigens conjugated to lipid or lipid-containing moieties |
摘要 |
The present invention provides a method of promoting a vigorous immune response to Type-2 T cell-independent antigens, such as bacterial polysaccharides, by the administration of a composition comprising a Type-2 T cell-independent antigen conjugated to a lipid or lipid-containing moeity, preferably, Lipo OspA. The composition promotes extensive class switching and memory to Type-2 T cell-independent antigens in immunocompetent and T cell-deficient hosts. |
申请公布号 |
AU3005499(A) |
申请公布日期 |
1999.10.11 |
申请号 |
AU19990030054 |
申请日期 |
1999.03.15 |
申请人 |
HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MED |
发明人 |
JAMES J. MOND;CLIFFORD M SNAPPER |
分类号 |
A61K39/385;A61K47/48;A61P37/04 |
主分类号 |
A61K39/385 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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