Therapeutic compounds

摘要

PCT No. PCT/AU94/00254 Sec. 371 Date Mar. 6, 1996 Sec. 102(e) Date Mar. 6, 1996 PCT Filed May 18, 1994 PCT Pub. No. WO94/26776 PCT Pub. Date Nov. 24, 1994A biologically-active peptide fragment of the Nef protein of human immunodeficiency virus is provided, pharmaceutical compositions comprising the peptide, analogs or derivatives of the peptide and therepeutic and screening methods which utilize the peptide and compositions which comprise them. The invention is particularly useful in the suppression of the immnune respons or in the suppression of symptoms of autoimmune disease.