发明名称 |
Detection of trinucleotide repeats by in situ hybridization |
摘要 |
Disclosed is a method of detecting a trinucleotide repeat expansion by in situ hybridization. The disclosed method uses a sample of nucleated cells, a labeled trinucleotide repeat-specific probe and detection of the hybridized probe by a means whose sensitivity distinguishes between the signal from probes hybridized to an expanded repeat and the signal from probes hybridized to a non-expanded repeat.
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申请公布号 |
US5962332(A) |
申请公布日期 |
1999.10.05 |
申请号 |
US19950570155 |
申请日期 |
1995.12.11 |
申请人 |
UNIVERSITY OF MASSACHUSETTS |
发明人 |
SINGER, ROBERT H.;TANEJA, KRISHAN L. |
分类号 |
C12Q1/68;(IPC1-7):G01N33/00;G01N21/76;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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