发明名称 |
Process for purifying recombinant human serum albumin |
摘要 |
The invention provides a process for purifying recombinant human serum albumin (rHSA) by heating a culture medium containing rHSA and the rHSA-producing host cello, feeding said heated solution upwardly into a fluidized bed in which adsorbent particles are suspended to effect contacting with the adsorbent particles and then recovering the adsorbed fraction containing the rHSA, and a composition comprising rHSA which shows a A35D/A280 ratio of below 0.015, when formulated into a 25% solution of said albumin.
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申请公布号 |
US5962649(A) |
申请公布日期 |
1999.10.05 |
申请号 |
US19950522089 |
申请日期 |
1995.08.31 |
申请人 |
YOSHITOMO PHARMACEUTICAL INDUSTRIES, LTD. |
发明人 |
NODA, MUNEHIRO;SUMI, AKINORI;OHMURA, TAKAO;YOKOYAMA, KAZUMASA |
分类号 |
C07K14/765;(IPC1-7):C07K1/16 |
主分类号 |
C07K14/765 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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