发明名称 Screening methods for cytokine inhibitors
摘要 The present invention provides a number of screening methods for evaluatiing compounds capable of suppressing cytokine production either in vitro or in vivo. The methods generally involve stimulating the production of a cytokine in a cell, exposing a portion of the cells to a putative cytokine modulating agent and determining subsequent levels of cytokine production in the cells. Additionally, the present invention provides certain compounds identified by this method.
申请公布号 US5962477(A) 申请公布日期 1999.10.05
申请号 US19980097441 申请日期 1998.06.15
申请人 ADOLOR CORPORATION 发明人 MAK, VIVIAN
分类号 A61K31/00;A61K31/341;A61K31/4174;A61K31/4422;A61K31/451;A61K31/522;A61K31/554;A61K31/585;G01N33/50;(IPC1-7):A61K31/445 主分类号 A61K31/00
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