发明名称 Prevention of breast cancer using selective estrogen receptor modulators.
摘要 The present invention provides a method of preventing breast carcinoma or cancer in a patient comprising administering a therapeutically effective amount of a compound having the structure (I) in which R<1> and R<2> are independently hydroxy or alkoxy of one to four carbon atoms; and R<3> and R<4> are independently methyl or ethyl, or R<3> and R<4>, taken together with the nitrogen atom to which they are attached, form a pyrrolidino, methyl-pyrrolidino, dimethylpyrrolidino, piperidino, morpholino, or hexamethyleneimino ring.
申请公布号 ZA9802818(B) 申请公布日期 1999.10.04
申请号 ZA19980002818 申请日期 1998.04.02
申请人 ELI LILLY AND COMPANY 发明人 ANDREW LAWRENCE GLASEBROOK
分类号 A61K31/4025;A61K31/4535;A61K31/5377;A61K31/55;A61P35/00;C07D333/64 主分类号 A61K31/4025
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