摘要 |
A pyridine derivative represented by formula (1) [wherein R<1> represents a halogen atom or a halogen-substituted lower alkyl; R<2> and R<3> respectively represent a hydrogen atom or a halogen atom; V represents a group: -C(=O)NH-, -NHC(=O) or NH-; and A represents A<1>, A<2> or A<3>: (groups in A<1> to A<3> respectively represent a hydrogen atom, a lower alkyl, a lower alkanoyl, hydroxyl, benzoyl or an oxo group)] or a pharmaceutically acceptable salt thereof. The compound (1) inhibits collagen production and is useful for preventing or treating fibrosis.
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申请人 |
OTSUKA PHARMACEUTICAL CO., LTD.;EDAMATSU, KOUJI;NAGAHAMA, TAKAO;HAYAKAWA, SATOSHI;KOJIMA, YUTAKA;SAKAMOTO, MAKOTO;YASUMURA, KOICHI |
发明人 |
EDAMATSU, KOUJI;NAGAHAMA, TAKAO;HAYAKAWA, SATOSHI;KOJIMA, YUTAKA;SAKAMOTO, MAKOTO;YASUMURA, KOICHI |