MUTATIONS RESPONSIBLE FOR ATTENUATION IN MEASLES VIRUS OR HUMAN RESPIRATORY SYNCYTIAL VIRUS SUBGROUP B

摘要

Isolated, recombinantly-generated, attenuated measles viruses and respiratory syncytial subgroup B viruses having defined attenuating mutations are described. Vaccines are formulated comprising such viruses and a physiologically acceptable carrier. The vaccines are used for immunizing an individual to induce protection against measles virus or respiratory syncytial subgroup B virus.