摘要 |
Multidrug resistant strains of Mycobacterium tuberculosis represent a considerable threat to public health worldwide. Resistance to isoniazid (INH), rifampicin or analogues thereof, or streptomycin, i.e. key components of anti-tuberculosis regimens, need frequently to be detected. The invention involves the detection of a mutation in either the katG gene (isoniazid resistance), the rpoB gene (rifampicin resistance) or rpsL gene (streptomycin resistance). |
申请人 |
INSTITUT PASTEUR, PARIS;MEDICAL RESEARCH COUNCIL, LONDON;ASSISTANCE PUBLIQUE, PARIS;UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI), PARIS;UNIVERSITE DE BERNE, BERN |
发明人 |
HEYM, BEATE;COLE, STEWART;YOUNG, DOUGLAS;ZHANG, YING;HONORE, NADINE;TELENTI, AMALIO;BODMER, THOMAS |