发明名称 Methods and means for the treatment of immune related diseases such as Graft vs. Host disease
摘要 The present invention provides novel means and methods for treating unwanted side reactions in transplantations, such as GvH and allograft rejection. The invention provides immunotoxines comprising an antibody and a toxic substance, whereby cocktails of such conjugates directed to different targets associated with one population of cells, wherein one target is chosen from CD3 or CD7. The preferred combination is a cocktail directed against both.
申请公布号 EP0945139(A1) 申请公布日期 1999.09.29
申请号 EP19980200917 申请日期 1998.03.23
申请人 KATHOLIEKE UNIVERSITEIT NIJMEGEN 发明人
分类号 A61K36/47;A61K39/395;A61K47/48;A61P37/00 主分类号 A61K36/47
代理机构 代理人
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