发明名称 Benzofluorene compounds, intermediates, compositions, and methods
摘要 The present invention provides compounds of formula I wherein R1 is -H, -OH, -O(C1-C4 alkyl), -OCO(C1-C6 alkyl), -OCOO(C1-C6 alkyl), -OCOAr, -OCOOAr, or -OSO2(C2-C6 alkyl); R2 is -OH, -O(C1-C4 alkyl), -OCO(C1-C6 alkyl), -OCOO(C1-C6 alkyl), -OCOAr, -OCOOAr, or -OSO2(C2-C6 alkyl); R3 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; and n is 2 or 3; or a pharmaceutically acceptable salt or solvate thereof.
申请公布号 US5958917(A) 申请公布日期 1999.09.28
申请号 US19970936671 申请日期 1997.09.24
申请人 ELI LILLY AND COMPANY 发明人 CROWELL, THOMAS ALAN;JONES, CHARLES DAVID;BRYANT, HENRY UHLMAN
分类号 C07D295/08;A61K31/075;A61K31/135;A61K31/40;A61K31/445;A61K31/535;A61K31/5375;A61K31/55;A61P3/02;A61P3/06;A61P19/10;A61P43/00;C07C39/12;C07C43/13;C07C69/18;C07C69/28;C07C217/18;C07C309/65;C07D207/06;C07D295/092;C07F7/18;(IPC1-7):C07D211/31;C07D211/00 主分类号 C07D295/08
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