HUMAN SPERM ACTIVATOR PEPTIDES

摘要

The present invention provides novel peptides that act as chemotactic factors for human sperm. The peptides comprise the amino acid sequence TMGFTAPRFPHY as well as analogs, homologues and derivatives. Also provided is a nucleic acid comprising a nucleotide sequence that encodes a novel sperm chemotactic peptide. Methods for diagnosing infertility caused by defects in sperm-egg interactions are also provided as well as methods for treating infertility wherein the infertility is due to a defect in sperm-egg interactions.