发明名称 |
Method for preparing a crystalline polymorph of terazosin monohydrochloride |
摘要 |
A crystalline polymorphous terazosine monohydrochloride is obtained by suspending and treating a crystalline addition product of terazosine hydrochloride and methanol in a polar solvent which is an alcohol with 2 to 6 carbon atoms or a ketone with 2 to 6 carbon atoms or a mixture thereof. The thus obtained crystalline polymorphous terazosine hydrochloride is characterized by a reduced hygroscopicity and solvent residue retention capacity.
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申请公布号 |
US5959108(A) |
申请公布日期 |
1999.09.28 |
申请号 |
US19980095483 |
申请日期 |
1998.06.10 |
申请人 |
CU CHEMIE UETIKON GMBH |
发明人 |
BAUER, CHRISTOPHE;GRUNENWALD, JEAN-MARIE |
分类号 |
C07D405/12;(IPC1-7):C07D241/04 |
主分类号 |
C07D405/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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