发明名称 |
IMMUNOSORBENT FOR DETECTION OF ANTIBODY TO HEPATITIS C VIRUS NUCLEAR PROTEIN IN BLOOD SERUM |
摘要 |
FIELD: medicine, biotechnology, immunology. SUBSTANCE: immunosorbent for detection of antibodies to hepatitis C virus nuclear protein is based on polymeric material. A layer of an antigen-synthetic peptide is applied on the base. As synthetic peptide the invention proposes a peptide corresponding to an antigenic determinant of hepatitis C virus nuclear protein of the following structure: NH<SB>2</SB>-Thr-Lys-Asn- -Thr-Asn-Arg-Arg-Pro-Gln-Asp-Val-Lys-Phe-Pro-Gly-Gly-Gly-Gln- -Ile-Val-Gly-Gly-Val-Tyr-Leu-Leu-Pro-Arg-Arg-Gly-Pro-Arg-Leu- -Gly-CO-NH<SB>2</SB>. Invention can be used in diagnosis of hepatitis C, for example, in diagnostic test-systems for detection of antibodies to hepatitis C virus nuclear protein. EFFECT: diagnosis of hepatitis C at the early stage. 7 tbl, 4 ex
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申请公布号 |
RU2138286(C1) |
申请公布日期 |
1999.09.27 |
申请号 |
RU19970109300 |
申请日期 |
1997.06.11 |
申请人 |
SANKT-PETERBURGSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INST;TOVARISHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU "VERTA";TOVARISHCHESTVO S OGRANICHENNO |
发明人 |
MUKOMOLOV S.L.;PLOTNIKOVA V.A.;ZHEBRUN A.B.;VERBOV V.N.;KOLOBOV A.A.;KAMPE-NEMM E.A.;SHPEN' V.M. |
分类号 |
A61K38/16;C07K14/00;G01N33/53;(IPC1-7):A61K38/16 |
主分类号 |
A61K38/16 |
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