发明名称 |
HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE |
摘要 |
A compound represented by formula (I), wherein ring M is a heterocyclic ring wherein formula (a) is one of -N=C<, -CO-N< or -CS-N<; R<a> and R<b> are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; Ring A and Ring B represent, independently, an optionally substituted homocyclic or heterocyclic ring, with the proviso that at least one of them is an optionally substituted heterocyclic ring; Ring C is an optionally substituted homocyclic or heterocyclic ring; Ring Z is an optionally substituted nitrogen-containing heterocyclic ring; and n is an integer from 1 to 6, or a salt thereof has a tachykinin receptor antagonistic activity in vitro, and is useful for preventing or treating depression, anxiety, manic-depressive illness or psychopathy. |
申请公布号 |
WO9947132(A2) |
申请公布日期 |
1999.09.23 |
申请号 |
WO1999JP01358 |
申请日期 |
1999.03.18 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;NATSUGARI, HIDEAKI;DOI, TAKAYUKI;IKEURA, YOSHINORI |
发明人 |
NATSUGARI, HIDEAKI;DOI, TAKAYUKI;IKEURA, YOSHINORI |
分类号 |
A61K31/4375;A61K31/55;A61K31/551;A61P1/00;A61P1/08;A61P11/06;A61P11/14;A61P13/00;A61P19/02;A61P25/18;A61P25/22;A61P25/24;A61P29/00;A61P43/00 |
主分类号 |
A61K31/4375 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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