| 摘要 |
<p>The present invention relates to the use of diagnostic ultrasound, and microbubble-based ultrasound contrast agents to accomplish non-invasive sub-harmonic (Fig. 11) aided pressure estimation (SHAPE) in the cavity of the heart, in other organs, and in major blood vessels. Diagnostic ultrasound provides non-invasive, real-time cross-sectional images, parameter estimations without ionizing radiation and without the disadvantages, and risks of invasive methods of imaging and measurement. SHAPE is a non-invasive, direct, and accurate method for pressure estimation utilizing sub-harmonic or ultra-harmonic signals from contrast agents (Fig. 2(b)). In light of the advantages of diagnostic ultrasound, SHAPE provides an economical alternative, a safe avenue, and an earlier timetable for assessing the clinical condition of patients, especially critically ill patients.</p> |
