摘要 |
<p>The invention concerns a novel use of VIP analogues for preventing and/or treating brain damage in a human foetus, baby or infant. Said VIP analogue is selected from the group consisting of cyclic VIP analogues and non-cyclic VIP derivatives of 28 amino acids comprising in N-terminal position a N-acetyl group, then Glu in position 8 (Glu8), Lys in position 12 (Lys12), polyclonal goat in position 17 (Nle17), Ala in position 19 (Ala19), X1 in position 21, X2 in position 25, Leu in position 26 (Leu26), Lys in position 27 and 28 (Lys27 and Lys28), Gly in position 29 and 30 (Gly29 and Gly30) and Thr in position 31 (Thr31), X1 representing Lys (Lys21) or Nle (Nle21) and X2 representing Asp (Asp25) or Asn (Asn25).</p> |