发明名称 |
Acellular pertussis vaccines and methods of preparation thereof |
摘要 |
Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70% of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B.pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material. <IMAGE> |
申请公布号 |
AU710538(B2) |
申请公布日期 |
1999.09.23 |
申请号 |
AU19960054941 |
申请日期 |
1996.05.02 |
申请人 |
CONNAUGHT LABORATORIES LIMITED |
发明人 |
RAAFAT E. F. FAHIM;JOHN R. VOSE;JOHN THIPPHAWONG;LUIS BARRETO;GAIL E. D. JACKSON;LARRY U. L. TAN;ANDREW HERBERT;MICHEL H KLEIN |
分类号 |
A61K39/00;A61K39/10;A61K39/116;A61K39/155;A61P31/04;A61P37/00;C07K14/235;(IPC1-7):C07K14/235 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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