发明名称 |
NOVEL MATRIX METALLOPROTEINASE INHIBITORS AND DOWN-REGULATORS |
摘要 |
The present invention relates to novel matrix metalloproteinase (MMP) inhibitors and down-regulators, to a process for the preparation of these inhibitors, to pharmaceutical compositions comprising these inhibitors/down-regulators, to the use of the novel MMP inhibitors for the manufacture of pharmaceutical and research preparations, to a method for inhibiting and down-regulating MMP-dependent conditions either in vivo or in vitro, to a method for inhibiting formation, synthesis, expression activations, and/or functions as well actions of matrix metalloproteinases, and to the use of the novel MMP inhibitors and down-regulators in biochemical isolation and purification procedures of matrix metalloproteinases.
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申请公布号 |
WO9947550(A1) |
申请公布日期 |
1999.09.23 |
申请号 |
WO1999FI00204 |
申请日期 |
1999.03.17 |
申请人 |
HELSINKI UNIVERSITY LICENSING LTD. OY;KOIVUNEN, ERKKI;SORSA, TIMO;SALO, TUULA |
发明人 |
KOIVUNEN, ERKKI;SORSA, TIMO;SALO, TUULA |
分类号 |
A61K38/00;A61P17/02;A61P19/00;A61P35/00;A61P35/04;A61P43/00;C07K7/06;C07K14/81;(IPC1-7):C07K7/06;A61K38/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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