发明名称 Naphthylazo inhibition of amyloidosis
摘要 PCT No. PCT/US96/16747 Sec. 371 Date Apr. 29, 1998 Sec. 102(e) Date Apr. 29, 1998 PCT Filed Oct. 18, 1996 PCT Pub. No. WO97/16194 PCT Pub. Date May 9, 1997Amyloid aggregation in animals is inhibited by administering a naphthylazo compound of formula (I), wherein R1 and R2 are hydrogen, alkyl, substituted alkyl, or complete a heterocyclic ring, R3 is hydrogen or alkyl, R4, R5, R6, and R7 are substitutent groups. The compounds are especially useful in preventing and treating Alzheimer's disease.
申请公布号 US5955472(A) 申请公布日期 1999.09.21
申请号 US19980066397 申请日期 1998.04.29
申请人 WARNER-LAMBERT COMPANY 发明人 HAYS, SHERYL JEANNE;LEVINE, III, HARRY;SCHOLTEN, JEFFERY DAVID
分类号 A61K31/655;A61K51/04;(IPC1-7):A01N43/42;C07C245/00 主分类号 A61K31/655
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