摘要 |
PROBLEM TO BE SOLVED: To provide a chromatographic separation of optical isomers in which a polysaccharide derivative chiral stationary phase is used as a chiral stationary phase and the mobile phase that has high separation performance, particularly giving a high fractionation productivity in the fractionation process, is used as a mobile phase. SOLUTION: In this chromatographic separation of optical isomers, a polysaccharide derivative chiral stationary phase is used as a chiral stationary phase, while a mixed solvent comprising a solvent selected from the group consisting of ethers, ketones, esters, amides and halogenated solvents, and hydrocarbon solvents is used as a mobile phase solvent. |