发明名称 |
Methods for treating gastrointestinal motility dysfunction using optically pure (-) cisapride |
摘要 |
The optically pure (-) isomer of cisapride is useful for the treatment of dyspepsia and such other conditions as may be related to the activity of (-) cisapride as a prokinetic agent, such as gastroparesis, constipation, post-operative ileus, and intestinal pseudo-obstruction, without the concomitant liability of adverse effects associated with the racemic mixture of cisapride. The (-) isomer of cisapride also exhibits longer duration of action than does racemic cisapride and is useful for treatment of disorders of the central nervous system.
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申请公布号 |
US5955477(A) |
申请公布日期 |
1999.09.21 |
申请号 |
US19960752984 |
申请日期 |
1996.11.21 |
申请人 |
SEPRACOR INC. |
发明人 |
GRAY, NANCY M.;YOUNG, JAMES W. |
分类号 |
C07D211/62;A61K31/445;A61K31/4468;A61P1/00;A61P1/08;A61P1/10;A61P1/14;(IPC1-7):A61K31/445 |
主分类号 |
C07D211/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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