发明名称 |
Antibodies to beta -amyloids or their derivatives and use thereof |
摘要 |
According to this invention, antibodies which are useful and novel in that they have binding specificity to beta -amyloids or derivatives thereof, namely recognize the N-terminal, the C-terminal or central portions of the beta -amyloids, respectively, were obtained. By combining these antibodies, determination methods by which the beta -amyloids could be determined sensitively and specifically are provided. These determination methods are useful for diagnosis of diseases to which the beta -amyloids or their derivatives are related (for example, Alzheimer's disease), and the antibodies of this invention are useful for the development of preventive-therapeutic compositions for Alzheimer's disease.
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申请公布号 |
US5955317(A) |
申请公布日期 |
1999.09.21 |
申请号 |
US19970986948 |
申请日期 |
1997.12.08 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
SUZUKI, NOBUHIRO;ODAKA, ASANO;KITADA, CHIEKO |
分类号 |
A61K38/00;C07K14/47;C07K16/18;C12P21/08;(IPC1-7):C12P21/04;C07K16/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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