发明名称 |
Monoclonal antibodies specific to VEGF receptors and uses thereof |
摘要 |
Monoclonal antibodies that specifically bind to an extracellular domain of a VEGF receptor and neutralize activation of the receptor are provided. In vitro and in vivo methods of using these antibodies are also provided.
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申请公布号 |
US5955311(A) |
申请公布日期 |
1999.09.21 |
申请号 |
US19980047807 |
申请日期 |
1998.03.25 |
申请人 |
IMCLONE SYSTEMS INCORPORATED |
发明人 |
ROCKWELL, PATRICIA;GOLDSTEIN, NEIL I. |
分类号 |
A61K38/00;C07K14/71;C07K16/28;C12P21/08;(IPC1-7):C12P21/06;C12P21/04;C12N15/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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