| 摘要 |
The present invention is directed to intraluminal shunt devices and methods of their use for delivering a drug or other fluid to a target vessel of a patient while also maintaining perfusion of blood through the vessel to reduce ischemia downstream of the vessel. The intraluminal shunt devices may generally include a primary elongate tubular member that is sized and dimensioned to be inserted into the target vessel, such as the right coronary artery. The primary tubular member includes at least one inner lumen which permits blood perfusion through the vessel. At least one secondary tubular member is provided which is in fluid communication with the primary tubular member. The secondary tubular member may be configured for drug or fluid delivery through the primary tubular member and into the vessel in either an anterograde or retrograde direction. Methods of using shunt devices are also described which generally include making an incision in the target vessel, inserting the proximal and distal ends of the primary tubular member into the target vessel via the incision, and selectively delivering the drug or fluid in either an anterograde or retrograde direction through the primary tubular member and into the vessel. |
