发明名称 PRODUCER CELLS FOR REPLICATION SELECTIVE VIRUSES IN THE TREATMENT OF MALIGNANCY
摘要 The invention includes producer cells for administering to a subject having tumor cells in order to kill tumor cells or prevent growth or spread of the tumor. The producer cell comprises an oncolytic virus which is capable of replicating in the producer cell. The producer cell is not capable of sustained survival in the body of the subject. The invention also includes methods of using these producer cells to treat a subject having tumor cells and making a medicament for use in such treatment.
申请公布号 WO9945783(A1) 申请公布日期 1999.09.16
申请号 WO1999US05466 申请日期 1999.03.12
申请人 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;MOLNAR-KIMBER, KATHERINE, L.;CAPARRELLI, DAVID, J.;KAISER, LARRY, R.;ALBELDA, STEVEN, M.;COUKOS, GEORGE 发明人 MOLNAR-KIMBER, KATHERINE, L.;CAPARRELLI, DAVID, J.;KAISER, LARRY, R.;ALBELDA, STEVEN, M.;COUKOS, GEORGE
分类号 A61K35/54;A61K35/76;A61K48/00;(IPC1-7):A01N63/00;C12N1/20;C12N15/00;C12P21/06 主分类号 A61K35/54
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