A method of assaying the growth hormone status of an individual by immuno-assay for the 150KDa Insulin-like Growth Factor ternary complex (IGF/IGFBP-3/ALS). Alternatively, a binary complex may be assayed. The method involves capturing the IGFBP complex with a first antibody coupled to a solid phase and detecting the complex with a second antibody coupled to a label. A set of monoclonal and polyclonal antibodies useful for the assay is also provided.
申请公布号
WO9946597(A1)
申请公布日期
1999.09.16
申请号
WO1999US05210
申请日期
1999.03.08
申请人
DIAGNOSTIC SYSTEMS LABORATORIES, INC.
发明人
KHOSRAVI, M., JAVAD;MISTRY, JEHANGIR;DIAMANDI, ANASTASIA