发明名称 |
INHIBITING SURFACE ENHANCED CRYSTALLIZATION OF AMORPHOUS PHARMACEUTICALS WITH ULTRATHIN COATINGS |
摘要 |
The present invention provides surface-stabilized amorphous pharmaceuticals comprising an amorphous pharmaceutical substrate coated with a biocompatible immobilizing material. Amorphous pharmaceutical substrates that are prone to surface enhanced crystallization benefit from the present coatings. The coated amorphous pharmaceuticals of the present invention maintain their amorphous state and, therefore, their solubility over extended periods of time, relative to uncoated pharmaceuticals.
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申请公布号 |
US2008233157(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
US20080053244 |
申请日期 |
2008.03.21 |
申请人 |
YU LIAN;DE VILLIERS MELGARDT M;WU TIAN |
发明人 |
YU LIAN;DE VILLIERS MELGARDT M.;WU TIAN |
分类号 |
A61K9/00;A61K31/405;A61K31/4422 |
主分类号 |
A61K9/00 |
代理机构 |
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地址 |
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