COMPUESTOS DERIVADOS DE N-(2-(HETARIL)ARIL)ARILSULFONAMIDAS Y N-(2-(HETARIL)HETARIL)ARILSULFONAMIDAS; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHO COMPUESTO; Y USO PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS DEL INTESTINO, ENFERMEDAD ALERGICA

摘要

Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.