发明名称 P-selectin ligand protein including tetrameric fusion proteins
摘要 A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
申请公布号 AU2975599(A) 申请公布日期 1999.09.15
申请号 AU19990029755 申请日期 1999.02.25
申请人 GENETICS INSTITUTE INC. 发明人 GLENN R. LARSEN;DIANNE S SAKO;XIAO-JIA CHANG;GEERTRUIDA M VELDMAN;DALE CUMMING;RAVINDRA KUMAR;GRAY SHAW;RAY CAMPHAUSEN;MONIQUE DAVIS
分类号 A61K38/00;C07K14/705;C12N9/10 主分类号 A61K38/00
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