发明名称 Polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolocarboxylic acid and method of obtaining them
摘要 The present invention provides a technique of selectively producing a polymorph crystal C of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid. The present invention also provides a method of producing the said polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid, which comprises crystallizing under the conditions defined by a specific temperature and a composition of a mixed solvent of methanol and water.
申请公布号 PL200710(B1) 申请公布日期 2009.01.30
申请号 PL19990338780 申请日期 1999.06.18
申请人 TEIJIN PHARMA LIMITED 发明人 MATSUMOTO KOICHI;WATANABE KENZO;HIRAMATSU TOSHIYUKI;KITAMURA MITSUTAKA
分类号 C07D277/56 主分类号 C07D277/56
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