发明名称 |
Process for synthesizing benzoic acids |
摘要 |
<p>A nucleophilic substitution reaction on optionally substituted dihalobenzenes is carried out in the presence of an optional catalyst followed by formation of and subsequent carboxylation of a Grignard reaction intermediate. In particular the present invention provides a process leading to optionally substituted hydroxybenzoic, alkanoyloxybenzoic, formyloxybenzoic and alkoxybenzoic acids from 1-substituted 2,6-dihalobenzenes. The invention also provides a process for the direct formation of an acyl chloride from a Grignard reagent by quenching with phosgene.</p> |
申请公布号 |
EP0941982(A2) |
申请公布日期 |
1999.09.15 |
申请号 |
EP19990301536 |
申请日期 |
1999.03.02 |
申请人 |
ROHM AND HAAS COMPANY |
发明人 |
CHONG, JOSHUA ANTHONY;ABDESAKEN, FEREYDON;SPANGLER, LORI ANN;JOSHI, SUDHIR RAMTIRTH;WU, CHARLES CHAO |
分类号 |
C07C51/15;C07C51/367;C07C51/58;C07C65/03;C07C65/21;C07C67/08;C07C69/07;C07C69/157;C07C69/24;(IPC1-7):C07C51/15;C07C63/70;C07C69/86 |
主分类号 |
C07C51/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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