摘要 |
A method and apparatus for growth and analysis of microbiological clones. A divider (6) is introduced into a layer of solid growth medium, separating the open surface of the medium into compartments. Appropriately diluted microbiological samples containing known strains of bacteria, yeast or virus infected bacteria are spread around the surface of the compartments. Glass beads can be used for spreading. Means for collecting beads contained within multiple compartments are provided. The divider is removed; means for preserving the structural integrity of the solid medium layer upon removal of the divider are provided. Colonies (in case of bacteria) or viral plaques (in case of virus infected bacteria) are allowed to form and subjected to further analyzes such as replica-plating or membrane lifts, which can now be performed on several samples simultaneously.
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