发明名称 STABILIZATION OF USEFUL PROTEIN AND USEFUL PROTEIN COMPOSITION
摘要 PROBLEM TO BE SOLVED: To provide a method for stabilizing useful protein by which a useful protein such as interferon is stabilized so as to be stably preserved without deactivation by mixing the aqueous solution of a compound having a base structure of arabic acid, with the useful protein. SOLUTION: The aqueous solution of a compound having a base structure of arabic acid of the formula (Galp is D-galactopyranose; Rhap is L- rhamnopyranose; Araf is L-arabofuranose; G.A. is D-glucuronic acid) in an amount regulated so that the objective composition may have a concentration of 0.01-10.0 wt.% is mixed with a useful protein comprising cytokines or the like such as interferon, and freeze-dried, and, if necessary, further reversed to the aqueous solution to stably preserve the useful protein without deactivating in the method for stabilizing the useful protein.
申请公布号 JPH11246597(A) 申请公布日期 1999.09.14
申请号 JP19980367567 申请日期 1998.12.24
申请人 TORAY IND INC 发明人 YAMADA MASANARI;WATANABE MASATOSHI;HARA NAOMI
分类号 C12P21/02;A61K9/08;A61K38/00;A61K38/21;A61K47/36;C07K14/555;C12R1/19;C12R1/91;(IPC1-7):C07K14/555 主分类号 C12P21/02
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