发明名称 TERPHENYL DERIVATIVE AND USE THEREOF
摘要 PROBLEM TO BE SOLVED: To obtain a cosmetic which can be expected to have effects for preventing and treating xeroderma, psoriasis, chapped skin, etc., where the degradation of hyaluronic acid is physiologically exasperated than that in a normal state, by adding the extract of Boletopsis Leucomelas as a component or an active ingredient. SOLUTION: This cosmetic contains an extract of Boletopsis Leucomelas or a terphenyl derivative of the formula (R1 -R4 are each OH or acetyl). The extract is obtained, for example, by immersing the lyophilized and ground product of the fruit bodies of Boletopsis Leucomelas, a mushroom originated from the family Thelephoraceae, in 5-30 times weight of an extraction solvent (especially water, ethanol, methanol or the like) usually at a temp. of 15-50 deg.C for 24 hr to 1 week, and subsequently removing impurities by a filtration method, a centrifugal separation method, etc.
申请公布号 JPH11246545(A) 申请公布日期 1999.09.14
申请号 JP19980049493 申请日期 1998.03.02
申请人 KANEBO LTD 发明人 SAKAI SHINGO;SAYO TETSUYA;INOUE SHINTARO;KAWAGISHI HIROKAZU;MURAKAMI HIROAKI
分类号 C07D307/91;A61K8/00;A61K8/49;A61K8/96;A61K8/97;A61K31/34;A61K31/343;A61K36/07;A61P17/00;A61P43/00;A61Q1/00;A61Q1/02;A61Q11/00;A61Q17/00;A61Q19/00;A61Q19/10 主分类号 C07D307/91
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