METHOD OF PRODUCING 3-AMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID DERIVATIVES AND 3-AMINO-1-NITRO-4-PHENYL-2-BUTANOL INTERMEDIATES

摘要

A process for producing a 3-amino-1-nitro-4-phenyl-2-butanol derivative represented by general formula (1) and a 3-amino-2-hydroxy-4-phenyl-butyric acid derivative derived therefrom. In said formula, R<1> and R<2> represent each independently hydrogen or an amino-protecting group. The process can industrially provide an optically active amino alcohol derivative as an intermediate for synthesizing medicines such as an immunopotentiating carcinostatic bestatin in a high yield safely, readily and highly selectively.