Method of Inducing An Anti-Retroviral Immune Response By Counter-Acting Retro-Virus Induced Anti-Apoptosis

摘要

A method of inducing an anti-retroviral immune response by counter-acting retro-virus induced anti-apoptosis is disclosed. The present invention relates, at least in part, to agents and methods for treating, inhibiting, vaccinating or controlling HIV. In certain non-limiting aspects, it relates to the reduction of viral load in an HIV-1 infected subject, while simultaneously developing immunological responsiveness within the subject toward HIV-1 that continues after the agent is removed or excreted from the subject's body.

主权项

1. A method of inducing an anti-retroviral immune response by counter-acting retro-virus induced anti-apoptosis comprising:
administering a therapeutic agent selected from the group consisting of deferiprone, ciclopirox, hydralazine and combinations thereof to a subject infected with HIV-1 in an effective amount and for a time period effective to allow infected cells to present HIV-1 antigens for immunological stimulation, followed by discontinuing administration of said deferiprone, ciclopirox or hydralazine after said effective time period, whereby viral load decreases during the administration and continues to decrease after the deferiprone is excreted from the subject's body.