发明名称 Human CRM1 Protein
摘要 A protein which comprises the sane or substantially the same amino acid sequence as that represented by SEQ ID NO:1, its partial peptide and their salts are disclosed. DNA encoding the protein or its partial peptide is also disclosed. The protein, its partial peptide or a salt thereof is an inhibitory factor of a transcription factor and, therefore, it is useful as medicine such as prophylactic and therapeutic drugs of, for example, tumors. The DNA is useful as a gene diagnosing drug. The antibody against the protein, etc. is also disclosed. The antibody is used for, for example, quantitative determination of the protein, etc. in a specimen fluid. The protein, etc. are also useful as a reagent for screening for compounds or their salts which promote the function of the protein, etc.
申请公布号 US5948883(A) 申请公布日期 1999.09.07
申请号 US19970975527 申请日期 1997.11.20
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 YOSHIDA, MINORU;HORINOUCHI, SUEHARU;NISHI, KAZUNORI
分类号 A61K38/00;C07K14/47;C12N15/12;(IPC1-7):C07K14/47 主分类号 A61K38/00
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