发明名称 |
AMINO ACID TREATMENT OF SEIZURES |
摘要 |
Methods for treating or preventing a seizure in a subject by administering to the subject a therapeutically effective amount of at least one D-amino acid or D-amino acid oxidase inhibitor are provided. In certain aspects, the method reduces the frequency, severity, and/or duration of one or more seizures in the subject. In particular aspects, at least one D-amino acid is administered to the subject before an onset of a seizure, during a seizure, or after a seizure to prevent further seizures. In certain aspects, at least one D-amino acid is administered to the subject prophylactically to prevent the occurrence of a seizure. In more particular aspects, the seizure is caused by epilepsy. |
申请公布号 |
US2016206583(A1) |
申请公布日期 |
2016.07.21 |
申请号 |
US201414914774 |
申请日期 |
2014.08.27 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
HARTMAN ADAM;SANTOS POLAN;HARDWICK J. MARIE |
分类号 |
A61K31/198;A61K31/423;A61K31/5513 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating or preventing a seizure in a subject, the method comprising administering to the subject a therapeutically effective amount of at least one D-amino acid. |
地址 |
Baltimore MD US |