发明名称 |
A DOUBLE CAPSULE FOR THE ADMINISTRATION OF ACTIVE PRINCIPLES IN MULTIPLE THERAPIES |
摘要 |
A pharmaceutical dosage form particularly suitable for the administration of active principles in multiple therapies is disclosed. The pharmaceutical dosage form is a double capsule wherein an internal capsule is placed inside an external one. Each internal and external capsule includes one or more active principles. A double capsule according to the invention is preferably used in triple or quadruple therapies against the microorganisms Helicobacter Pylori. Advantages of this pharmaceutical dosage form consist in provididng a simple posology for administration of two and more active principles, allowing the active principles to activate at the right intervals of time and in the pre-established quantities, and preventing interactions between active principles. In a preferred embodiment of the invention, the pharmaceutical dosage form has an external capsule containing bismuth subcitrate and metronidazole, and an internal capsule containing tetracycline and optionally omeprazole, which is used in therapy for eradication of Helicobacter pylori. |
申请公布号 |
WO9930693(A3) |
申请公布日期 |
1999.09.02 |
申请号 |
WO1998EP08167 |
申请日期 |
1998.12.14 |
申请人 |
AXCAN PHARMA INC.;ISTITUTO PIRRI S.R.L.;SANSO', GIOVANNI |
发明人 |
SANSO', GIOVANNI |
分类号 |
A61K9/48;A61K9/64;A61K31/19;A61K31/4164;A61K31/426;A61K31/4439;A61K31/60;A61K31/65;A61K31/7048;A61K33/24;A61K47/02;A61K47/10;A61K47/12;A61K47/14;A61K47/26;A61K47/36;A61K47/38;A61K47/44;A61P31/04 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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