发明名称 EIN PROTEIN, DAS SPEZIFISCHE DNA-STRUKTUREN ERKENNT, UND SEINE VERWENDUNGEN
摘要 DNA structure specific recognition protein of eukaryotic origin and DNA encoding such a factor, as well as probes specific for DNA structure specific recognition protein or DNA encoding it and methods of detecting DNA structure specific recognition protein in eukaryotic cells. In particular, a mammalian cellular factor that selectively recognizes and binds DNA damaged or modified by a drug (the anticancer drug, cis-diamminedichloroplatinum (II) or cisplatin) has been identified.
申请公布号 DE69229681(D1) 申请公布日期 1999.09.02
申请号 DE1992629681 申请日期 1992.12.18
申请人 MASSACHUSETTS INSTITUTE OF TECHNOLOGY 发明人 DONAHUE, BRIAN;TONEY, JEFFREY;ESSIGMANN, JOHN;LIPPARD, STEPHEN;PIL, PIETER;BRUHN, SUZANNE;BROWN, STEVEN;KELLETT, PATTI
分类号 C12N15/09;A61K38/00;C07K14/39;C07K14/435;C07K14/47;C07K16/00;C07K16/18;C12P21/02;C12P21/08;C12Q1/68 主分类号 C12N15/09
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